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Choice of transcriptional direction from each D4Z4 unit is an additional requirement for DUX4 production and having FSHD

Home / FSHD Research / Choice of transcriptional direction from each D4Z4 unit is an additional requirement for DUX4 production and having FSHD

Posted on: Apr 20, 2012

FSHD research teams in Seattle, Rochester and Leiden add to the existing FSHD model loss of heterochromatin at D4Z4 and the presence of a specific haplotype on chromosome 4 are necessary but not sufficient for DUX4 expression in PLoS ONE. Choice of transcriptional direction from each D4Z4 unit is an additional requirement for DUX4 production and having FSHD More

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